You may think that you fuck your blood type , but did you acknowledge that there are in fact 35 stock group scheme in humans ? These include well - known system such as ABO and the Rh organisation ( formerly known as ‘ Rhesus ’ ) .
Advances in research technologies in the past few years have made it potential to place three new blood group systems : LangereisandJunior , key in 2012 , andVel , discovered a year later in 2013 . All three were named after the patient role in whom they were first discovered .
In Japan , there are around 2,500 people who are Langereis disconfirming . Although Langereis - negative people have been found across the globe , their entire numbers are n’t known . Also in Japan , there are some 50,000 citizenry who are Junior negative . This bloodline type is think to be rare in the rest of the world , although there are some Junior - negative people among European gypsy community . And around 400,000 people – mostly in Europe and the USA – are think to be Vel negative .
trap down the antigens and antibodies in each organisation – and developing a speedy in - infirmary test for them – was an important step for transfusion medication , because all three are ‘ clinically substantial ’ . This is because they will cause a dangerous reaction if instill into a patient who has made an antibody against ‘ positive ’ blood .
The antibody multitude make against Vel , designated ‘ anti - Vel ’ , is the most dreaded . Transfusion doctors have have it off of its being since the early 1950s , when ‘ Patient Vel ’ , a 66 - year - old cleaning lady , violently rejected the blood she had receive .
However , the antibody was such a scarce resourcefulness – not everyone who is Vel damaging will make it , even on vulnerability to positive roue – that Vel - negative stock was impossible to riddle for on more than a small scale . That all changed last year when two international teams separately identified the familial mutation responsible for the drop antibody : patient and donor blood can now be screen for it with a wide-eyed DNA test .
It ’s still potential that other parentage chemical group system of rules or antigens – so rare they have n’t yet surfaced – may emerge . Nicole Thornton , Head of Red Cell Reference at theInternational Blood Group Reference Laboratory ( IBGRL)in Filton , near Bristol in England , thinks there are undiscovered organization out there . Professor Bryan Ballif – who with colleague identified the molecular basis of Langereis and Junior , and who was in one of the teams who produce the trial for Vel – think there could be as many as ten .
This articlefirst appear on Mosaicand is republished here under Creative Commons license . look-alike byMate Marschalkounder Creative Commons license .
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